作者:王瑞,曾輝,李琰,王娜,張健慧,張金文,王偉,劉俊峯
【關鍵詞】 非小細胞肺癌;XRCC,2基因;易感性;遺傳多態性
Association between gene polymorphism of XRCC 2 and susceptibility of nonsmall cell lung cancers
1Department of Thoracic Surgery, Fourth Affiliated Hospital, Hebei Medical University, 2Laboratory of Molecular Biology, Hebei Cancer Institute, Shijiazhuang 050011, China, 3National Center for AIDS Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China, 4Operation Room, Thoracic Hospital of Hebei Province, Shijiazhuang 050011, China, 5Department of Surgery, Chengan County Hospital of Hebei Province, Handan 056700, China
【Abstract】 AIM: To observe the association between the risk of nonsmall cell lung cancers and polymorphism and gene frequency of XRCC 2 C41657T and G4234C in north Chinese Han population. METHODS: The single nucleotide polymorphisms (SNPs) of the C41657T and G4234C in the XRCC 2 gene were genotyped by PCRRFLP analysis in 226 nonsmall cell lung cancer patients and 300 healthy controls. RESULTS: There was XRCC 2 gene C41657T and G4234C polymorphism in north Chinese Han population. The genotype and allelotype distributions of the XRCC 2 C41657T and G4234C SNPs in the nonsmall cell lung cancer patients were not significantly different from those of the controls (all P
XRCC 2 基因多態性與非小細胞肺癌易感性的關係
學問君
人氣:1.77W
猜你喜歡
- 1中性粒細胞在大鼠急性重症胰腺炎肺損傷中的作用機制
- 2肺癌發病和心理健康有關聯性
- 3阿司匹林調節小鼠移植性肝癌的基因表達
- 4銀屑病中細胞凋亡相關基因bcl-2、Fas、bax的檢測
- 5DOC2抑制對宮頸癌SiHa細胞系的生長
- 6鹼性成纖維細胞生長因子對視網膜Müller細胞表達血管內皮生長因
- 7細胞因子與牙槽骨吸收關係的研究進展
- 8RNA干擾對血管內皮生長因子在人宮頸癌細胞系Hela細胞中表達及細
- 9鹼性成纖維細胞生長因子在前列腺癌和良性前列腺增生組織中表達的
- 10經濟系統的複雜性與經濟波動的多因性分析
- 11Goosecoid基因突變及環境危險因素與先天性小耳畸形的關係
- 12新生兒病毒感染免疫細胞與細胞因子研究
- 13試論骨科輻射效應的線性與非線性關係
- 14慢性阻塞性肺疾病毒感染危險因素
- 15HBV全基因組克隆轉染細胞系的建立
最近更新
- 1區域性服務貿易規則與多邊規則之關係論文
- 2非線性編輯系統的關鍵:專業非線性編輯板卡
- 3小兒難治性肺炎臨牀病因與護理觀察
- 4腎癌MMPS表達與MVD的相關性研究
- 5甲胎蛋白促使人肝癌細胞逃避淋巴細胞的攻擊
- 6區域性服務貿易規則與多邊規則之關係
- 7復發及難治急性髓細胞白血病病人多藥耐藥基因檢測及意義
- 8重症急性胰腺炎大鼠DDFA對肺損傷細胞凋亡及Bax, Bcl
- 9OA系統易用性的重要性
- 10關於非貨幣性交易的審計
- 11慣性與慣性狀態
- 12樹舌多糖GF對HepA瘤細胞C-myc基因表達的影響
- 13腺病毒介導凋亡素基因對人膽管癌細胞凋亡的研究
- 14慢性阻塞性肺疾病患者誘導痰IL8、TNFα水平和炎症細胞的分佈
- 15成纖維細胞系及生物學特性分析論文